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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC3
All Species:
31.82
Human Site:
Y957
Identified Species:
50
UniProt:
Q9UQE7
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQE7
NP_005436.1
1217
141542
Y957
P
Q
E
A
F
E
K
Y
Q
T
L
S
L
K
Q
Chimpanzee
Pan troglodytes
XP_508031
1374
158072
Y1114
P
Q
E
A
F
E
K
Y
Q
T
L
S
L
K
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851818
1228
142683
Y968
P
Q
E
A
F
E
K
Y
Q
T
L
S
L
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9CW03
1217
141537
Y957
P
Q
E
A
F
E
K
Y
Q
T
L
S
L
K
Q
Rat
Rattus norvegicus
P97690
1191
138430
K924
H
D
T
K
E
L
E
K
M
T
N
R
Q
G
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512851
1238
143475
Y978
P
Q
E
A
F
E
K
Y
Q
T
L
S
L
K
Q
Chicken
Gallus gallus
Q90988
1189
134923
D926
K
Y
Q
Q
E
T
A
D
A
S
S
T
L
D
K
Frog
Xenopus laevis
O93309
1209
140704
P950
I
R
E
L
G
S
L
P
Q
E
A
F
E
K
Y
Zebra Danio
Brachydanio rerio
NP_999854
1216
141517
Y957
P
Q
E
A
F
E
K
Y
Q
T
L
T
L
K
Q
Tiger Blowfish
Takifugu rubipres
NP_001027798
1217
141541
Y957
P
Q
E
A
F
E
K
Y
Q
T
L
T
L
K
Q
Fruit Fly
Dros. melanogaster
NP_523374
1200
140018
T940
N
E
K
I
D
E
C
T
E
K
I
A
S
L
G
Honey Bee
Apis mellifera
XP_393700
1202
139436
T939
Q
Q
K
I
V
E
C
T
Q
K
I
T
E
L
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202053
792
92535
S542
I
V
D
T
D
T
I
S
T
K
I
L
S
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SN90
1171
132296
I898
Q
E
K
C
L
Q
K
I
S
D
M
K
L
D
R
Baker's Yeast
Sacchar. cerevisiae
P47037
1230
141318
F969
E
D
A
L
V
N
D
F
S
D
I
T
S
D
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
N.A.
99
N.A.
99.9
97.2
N.A.
97.5
23.3
95.8
95.1
94.9
53.4
55.4
N.A.
40.1
Protein Similarity:
100
88.5
N.A.
99
N.A.
100
97.4
N.A.
98
46.5
97.6
97.5
97.3
73.2
72.9
N.A.
53.9
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
100
6.6
20
93.3
93.3
6.6
20
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
100
33.3
26.6
100
100
40
40
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47
57.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
47
0
0
7
0
7
0
7
7
0
0
0
% A
% Cys:
0
0
0
7
0
0
14
0
0
0
0
0
0
0
0
% C
% Asp:
0
14
7
0
14
0
7
7
0
14
0
0
0
20
0
% D
% Glu:
7
14
54
0
14
60
7
0
7
7
0
0
14
7
0
% E
% Phe:
0
0
0
0
47
0
0
7
0
0
0
7
0
0
0
% F
% Gly:
0
0
0
0
7
0
0
0
0
0
0
0
0
7
14
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
14
0
0
14
0
0
7
7
0
0
27
0
0
0
0
% I
% Lys:
7
0
20
7
0
0
54
7
0
20
0
7
0
54
7
% K
% Leu:
0
0
0
14
7
7
7
0
0
0
47
7
60
14
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
14
% M
% Asn:
7
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% N
% Pro:
47
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
14
54
7
7
0
7
0
0
60
0
0
0
7
0
54
% Q
% Arg:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
7
% R
% Ser:
0
0
0
0
0
7
0
7
14
7
7
34
20
0
0
% S
% Thr:
0
0
7
7
0
14
0
14
7
54
0
34
0
0
0
% T
% Val:
0
7
0
0
14
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
47
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _